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WebJan 23, 2024 · The metabolic substrates that cells use provide more than bioenergetics and help to shape cellular identity. Understanding the connection between metabolism and cell fate could usher in a wave of new therapies. Increasing evidence implicates metabolic pathways as key regulators of cell fate and function. Although the metabolism of … WebApr 11, 2024 · This method enables the introduction of antigen glycans onto cancer cells to induce immune responses through antibody recruiting. The caging strategy prevents the capture of α-rhamnose (an antigen glycan) by their endogenous antibodies during the introduction of the glycan to the targeted cell surface, and subsequent uncaging … good books to read for 13 year old boys
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WebMitophagy is a cargo-specific autophagic process that recycles damaged mitochondria to promote mitochondrial turnover. PTEN-induced putative kinase 1 (PINK1) mediates the canonical mitophagic pathway. However, the role of PINK1 in diseases where mitophagy has been purported to play a role, such as colorectal cancer, in unclear.Our results here … WebApr 10, 2024 · A nonhuman primate NASH model is established to mimic human disease. •. DT-109 attenuates steatohepatitis, inflammation, and fibrosis in NASH. •. DT-109 … WebApr 11, 2024 · Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and … health information leak into code